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公开(公告)号：US20190070278A1
公开(公告)日：2019-03-07
申请号：US16179159
申请日：2018-11-02
申请人： SOTIO a.s.
发明人： Jitka Fucikova , Lenka Koci , Katerina Pokorna , Iva Truxova , Irena Moserova , Daniela Rozkova , Radek Spisek
CPC分类号： A61K39/0011 , A01N1/0221 , A01N1/0278 , A61K35/13 , A61K2039/5152 , C12N5/0693
摘要： Described herein is a reliable method for preparing a potent vaccine useful for immunotherapy comprising the step of cryopreserving a population of cells undergoing immunogenic cell death, and using such cells to activate dendritic cells for use in immunotherapy. In a specific embodiment, the method comprises cryopreserving cancer cells undergoing cell death, which can be used to prepare a pharmaceutical composition for immunotherapy against cancer.
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2.发明授权Cryopreservation of apoptotic cancer cells for use in immunotherapy against cancer 有权凋亡癌细胞的冷冻保存用于免疫治疗癌症公开(公告)号：US09562219B2
公开(公告)日：2017-02-07
申请号：US14142448
申请日：2013-12-27
申请人： SOTIO a.s.
发明人： Jitka Fucikova , Lenka Koci , Katerina Pokorna , Iva Truxova , Irena Moserova , Daniela Rozkova , Radek Spisek
CPC分类号： A61K39/0011 , A01N1/0221 , A01N1/0278 , A61K35/13 , A61K2039/5152 , C12N5/0693
摘要： Described herein is a reliable method for preparing a potent vaccine useful for immunotherapy comprising the step of cryopreserving a population of cells undergoing immunogenic cell death, and using such cells to activate dendritic cells for use in immunotherapy. In a specific embodiment, the method comprises cryopreserving cancer cells undergoing cell death, which can be used to prepare a pharmaceutical composition for immunotherapy against cancer.
摘要翻译： 本文描述的是制备用于免疫治疗的有效疫苗的可靠方法，包括冷冻保存经历免疫原性细胞死亡的细胞群的步骤，以及使用这样的细胞激活用于免疫治疗的树突状细胞。 在具体实施方案中，该方法包括冷冻保存经历细胞死亡的癌细胞，其可用于制备用于免疫治疗癌症的药物组合物。
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3.发明申请CRYOPRESERVATION OF APOPTOTIC CANCER CELLS FOR USE IN IMMUNOTHERAPY AGAINST CANCER 有权胃癌免疫治疗用于癌症免疫治疗的CRYOPRESER公开(公告)号：US20150184130A1
公开(公告)日：2015-07-02
申请号：US14142448
申请日：2013-12-27
申请人： SOTIO a.s.
发明人： Jitka Fucikova , Lenka Koci , Katerina Pokorna , Iva Truxova , Irena Moserova , Daniela Rozkova , Radek Spisek
CPC分类号： A61K39/0011 , A01N1/0221 , A01N1/0278 , A61K35/13 , A61K2039/5152 , C12N5/0693
摘要： Described herein is a reliable method for preparing a potent vaccine useful for immunotherapy comprising the step of cryopreserving a population of cells undergoing immunogenic cell death, and using such cells to activate dendritic cells for use in immunotherapy. In a specific embodiment, the method comprises cryopreserving cancer cells undergoing cell death, which can be used to prepare a pharmaceutical composition for immunotherapy against cancer.
摘要翻译： 本文描述的是制备用于免疫治疗的有效疫苗的可靠方法，包括冷冻保存经历免疫原性细胞死亡的细胞群的步骤，以及使用这样的细胞激活用于免疫治疗的树突状细胞。 在具体实施方案中，该方法包括冷冻保存经历细胞死亡的癌细胞，其可用于制备用于免疫治疗癌症的药物组合物。
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公开(公告)号：US10155033B2
公开(公告)日：2018-12-18
申请号：US15866896
申请日：2018-01-10
申请人： SOTIO a.s.
发明人： Jitka Fucikova , Lenka Koci , Katerina Pokorna , Iva Truxova , Irena Moserova , Daniela Rozkova , Radek Spisek
摘要： Described herein is a reliable method for preparing a potent vaccine useful for immunotherapy comprising the step of cryopreserving a population of cells undergoing immunogenic cell death, and using such cells to activate dendritic cells for use in immunotherapy. In a specific embodiment, the method comprises cryopreserving cancer cells undergoing cell death, which can be used to prepare a pharmaceutical composition for immunotherapy against cancer.
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公开(公告)号：US09895430B2
公开(公告)日：2018-02-20
申请号：US15388972
申请日：2016-12-22
申请人： SOTIO a.s.
发明人： Jitka Fucikova , Lenka Koci , Katerina Pokorna , Iva Truxova , Irena Moserova , Daniela Rozkova , Radek Spisek
CPC分类号： A61K39/0011 , A01N1/0221 , A01N1/0278 , A61K35/13 , A61K2039/5152 , C12N5/0693
摘要： Described herein is a reliable method for preparing a potent vaccine useful for immunotherapy comprising the step of cryopreserving a population of cells undergoing immunogenic cell death, and using such cells to activate dendritic cells for use in immunotherapy. In a specific embodiment, the method comprises cryopreserving cancer cells undergoing cell death, which can be used to prepare a pharmaceutical composition for immunotherapy against cancer.
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公开(公告)号：US20200147191A1
公开(公告)日：2020-05-14
申请号：US16730667
申请日：2019-12-30
申请人： SOTIO a.s.
发明人： Jitka Fucikova , Lenka Koci , Katerina Pokorna , Iva Truxova , Irena Moserova , Daniela Rozkova , Radek Spisek
摘要： Described herein is a reliable method for preparing a potent vaccine useful for immunotherapy comprising the step of cryopreserving a population of cells undergoing immunogenic cell death, and using such cells to activate dendritic cells for use in immunotherapy. In a specific embodiment, the method comprises cryopreserving cancer cells undergoing cell death, which can be used to prepare a pharmaceutical composition for immunotherapy against cancer.
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公开(公告)号：US10561717B2
公开(公告)日：2020-02-18
申请号：US16179159
申请日：2018-11-02
申请人： SOTIO a.s.
发明人： Jitka Fucikova , Lenka Koci , Katerina Pokorna , Iva Truxova , Irena Moserova , Daniela Rozkova , Radek Spisek
摘要： Described herein is a reliable method for preparing a potent vaccine useful for immunotherapy comprising the step of cryopreserving a population of cells undergoing immunogenic cell death, and using such cells to activate dendritic cells for use in immunotherapy. In a specific embodiment, the method comprises cryopreserving cancer cells undergoing cell death, which can be used to prepare a pharmaceutical composition for immunotherapy against cancer.
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公开(公告)号：US20180125956A1
公开(公告)日：2018-05-10
申请号：US15866896
申请日：2018-01-10
申请人： SOTIO a.s.
发明人： Jitka Fucikova , Lenka Koci , Katerina Pokorna , Iva Truxova , Irena Moserova , Daniela Rozkova , Radek Spisek
CPC分类号： A61K39/0011 , A01N1/0221 , A01N1/0278 , A61K35/13 , A61K2039/5152 , C12N5/0693
摘要： Described herein is a reliable method for preparing a potent vaccine useful for immunotherapy comprising the step of cryopreserving a population of cells undergoing immunogenic cell death, and using such cells to activate dendritic cells for use in immunotherapy. In a specific embodiment, the method comprises cryopreserving cancer cells undergoing cell death, which can be used to prepare a pharmaceutical composition for immunotherapy against cancer.
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