A polymeric remote seal system is provided for coupling a single-use container to a pressure measurement instrument. The polymeric remote seal system includes a process-side coupling, an instrument-side coupling and a fluidic coupling therebetween. The process-side coupling is configured to couple to the single-use container and is formed of a radiation sterilizable polymer. The process-side coupling has a process-side deflectable diaphragm that is configured to deflect in response to pressure within the single-use container. The instrument-side coupling is configured to couple to the pressure measurement instrument and is formed of a radiation sterilizable polymer. The instrument-side coupling is configured to fluidically convey fluid pressure to an isolation diaphragm of the pressure measurement instrument. Tubing fluidically couples the process-side coupling to the instrument-side coupling.