A device for lubricating the cylinders of a roll stand, in particular for roll nip lubrication in a roll stand for strip-shaped rolling stock. A mixture of water and oil is produced by a mixing and spraying device (1). The mixture is sprayed onto at least one of the cylinders (2) of the roll stand and/or to the surface of the rolling stock (3). The mixing and spraying device (1) include an arrangement of several nozzle mixer units (4). Water is guided thereto by a first supply line (5) and oil is guided thereto by a second supply line (6).