Concepts and technologies are disclosed herein for point-of-sale customization service. A processor executing a point-of-sale customization service can receive a unique identifier associated with a user device detected in a proximity of a computing device. The processor can query preferences stored in a data store using the unique identifier and identify point-of-sale preferences associated with the user device based upon the querying. The processor can transmit the point-of-sale preferences to the computing device to apply to a transaction.