发明授权
US09573919B2 Peroxisome proliferator-activated receptor (PPAR) activator, and drugs, supplements, functional foods and food additives using the same
有权
过氧化物酶体增殖物激活受体（PPAR）激活剂，以及药物，补充剂，功能食品和使用其的食品添加剂
- 专利标题： Peroxisome proliferator-activated receptor (PPAR) activator, and drugs, supplements, functional foods and food additives using the same
- 专利标题（中）： 过氧化物酶体增殖物激活受体（PPAR）激活剂，以及药物，补充剂，功能食品和使用其的食品添加剂
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申请号： US11800637申请日： 2007-05-07
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公开(公告)号： US09573919B2公开(公告)日： 2017-02-21
- 发明人: Takao Sasaki
- 申请人： Takao Sasaki
- 申请人地址： JP Kyoto
- 专利权人： ARKRAY, Inc.
- 当前专利权人： ARKRAY, Inc.
- 当前专利权人地址： JP Kyoto
- 代理机构： Morgan, Lewis & Bockius LLP
- 优先权： JP2004-324015 20041108
- 主分类号： C07D311/30
- IPC分类号： C07D311/30 ; A61K31/352 ; A61K36/752
摘要：
The present invention provides a peroxisome proliferator-activated receptor (PPAR) activator, which is free from the problem of side effects, can be taken over a long term and has no characteristics taste. Nobiletin is employed as a PPAR activator. Nobiletin has an excellent PPAR activity and has an excellent adiponectin secretion-promoting effect, and is contained in a large amount in citrus fruits, in particular, in Shiikuwasha (Citrus depressa HAYATA) indigenous to Okinawa (Japan). Since citrus fruits have been consumed for many years, the safety of nobiletin has been proven and besides, nobiletin has a low calorie content. Therefore, it can be taken over a long term. Moreover, because of being tasteless and odorless, nobiletin would not damage the unique taste of a food when added thereto. Therefore, it can be added to foods and taken.
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