公开(公告)号：US08802723B2

公开(公告)日：2014-08-12

申请号：US11795774

申请日：2006-01-20

申请人： Takao Sasaki

发明人： Takao Sasaki

IPC分类号： A01N43/16 ,  A61K31/37 ,  A61K8/49 ,  A61Q19/00 ,  A23L1/30 ,  A61K36/752

CPC分类号： A61K36/752 ,  A23L33/105 ,  A23V2002/00 ,  A61K8/498 ,  A61K31/37 ,  A61K2800/92 ,  A61Q19/00 ,  A23V2200/304 ,  A23V2200/328 ,  A23V2200/326 ,  A23V2200/318

摘要： A metabolic syndrome relieving agent that is free from a problem of side effects and can be taken for a long term is provided. Aurapten is used as an agent for relieving a metabolic syndrome. Since aurapten has functions of activating PPARα and PPARγ, promoting the secretion of adiponectin in adipocytes and inhibiting the generation of VLDLs in hepatic cells, it is possible to prevent or treat diseases such as insulin resistance, hyperinsulinism, type 2 diabetes, obesity, visceral fat obesity, hypertension, hyperlipemia, arteriosclerosis and the like and thus prevent or treat the metabolic syndrome. Also, as understood from the fact that citrus fruits such as a hassaku orange, a sweet summer orange or the like containing aurapten have been eaten for many years, they have no problems in terms of safety and have a low calorie content, and therefore, they can be taken for a long term. Further, since aurapten is tasteless and odorless, it does not impair the unique taste of a food when added to this food, so that it can be added to foods and taken.

摘要翻译： 提供了不存在副作用问题并可长期服用的代谢综合征缓解剂。 Aurapten用作缓解代谢综合征的药物。 由于aurapten具有激活PPARα和PPARγ的功能，促进脂肪细胞中脂联素的分泌和抑制肝细胞中VLDL的产生，可以预防或治疗诸如胰岛素抵抗，高胰岛素血症，2型糖尿病，肥胖，内脏脂肪 肥胖症，高血压，高脂血症，动脉硬化等，从而预防或治疗代谢综合征。 另外，由于柑橘类水果如橙子，含有刺槐的甜夏夏等已经吃了多年，因此在安全性方面没有问题，卡路里含量低， 他们可以长期服用。 此外，由于无纺布是无味无味的，因此当添加到食品中时不会损害食品的独特味道，从而可以将其加入到食品中并被摄取。

公开(公告)号：US20120248027A1

公开(公告)日：2012-10-04

申请号：US13508704

申请日：2010-12-16

申请人： Takao Sasaki ,  Tomoko Mitsuhata ,  Kentaro Takagi ,  Katsufumi Oto

发明人： Takao Sasaki ,  Tomoko Mitsuhata ,  Kentaro Takagi ,  Katsufumi Oto

IPC分类号： B01D71/56 ,  B01D69/10 ,  C08L77/00

CPC分类号： B01D71/56 ,  B01D65/003 ,  B01D69/12 ,  B01D2323/12 ,  B01D2325/30 ,  C02F1/44 ,  C08J7/047 ,  C08J2477/00

摘要： A composite semipermeable membrane comprising a porous support membrane on which a separating functional polyamide layer resulting from the polycondensation reaction of polyfunctional aromatic amines with polyfunctional acid halides is formed, wherein the separating functional polyamide layer has carboxy groups, amino groups, phenolic hydroxyl groups, and azo groups, wherein XA, the ratio of the amino groups (molar equivalent of the amino groups/(molar equivalent of the azo groups+molar equivalent of the phenolic hydroxyl groups+molar equivalent of the amino groups)) on a feed water contact surface of the separating functional polyamide layer (an A surface), is in the range 0.5 or less, and XB, the ratio of the amino groups (molar equivalent of the amino groups/(molar equivalent of the azo groups+molar equivalent of the phenolic hydroxyl groups+molar equivalent of the amino groups)) on a permeate-side surface of the separating functional polyamide layer (a B surface), i.e., the opposite side to the A surface, is in the range of 0.5 to 1. The present invention provides a composite semipermeable membrane that achieves a balance between high solute removal properties and a high permeate flow rate and has high organic-solvent resistance, and a method for producing same.

摘要翻译： 一种复合半透膜，包括多孔支撑膜，其上形成由多官能芳族胺与多官能酰卤的缩聚反应产生的分离功能聚酰胺层，其中分离官能聚酰胺层具有羧基，氨基，酚羟基和 偶氮基团，其中XA，原料水接触表面（氨基的摩尔当量/（偶氮基团的摩尔当量+酚羟基的摩尔当量+氨基的摩尔当量））的比例 的分离功能性聚酰胺层（A表面）的范围为0.5以下，XB为氨基（氨基的摩尔当量/（偶氮基的摩尔当量+酚的摩尔当量） 羟基+氨基摩尔当量））在分离功能聚酰胺层（B面）的渗透侧表面上，即相反的 在一侧的A表面，在0.5〜1的范围内。本发明提供一种复合半透膜，其在高溶质除去性和高渗透流量之间达到平衡，并且具有高的有机溶剂耐性， 用于生产。

公开(公告)号：US07641054B2

公开(公告)日：2010-01-05

申请号：US11666752

申请日：2005-11-04

申请人： Takao Sasaki ,  Hiroki Tomioka ,  Koji Nakatsuji

发明人： Takao Sasaki ,  Hiroki Tomioka ,  Koji Nakatsuji

IPC分类号： B01D29/00 ,  B01D39/14 ,  B01D67/00

CPC分类号： B01D67/0088 ,  B01D65/10 ,  B01D67/0093 ,  B01D69/02 ,  B01D69/122 ,  B01D69/125 ,  B01D71/56 ,  B01D2323/30 ,  C02F1/441 ,  C02F2103/08 ,  Y02A20/131

摘要： A composite semipermeable membrane, which comprises a separating functional layer comprising a reactant of polyfunctional amine with polyfunctional acid halide, wherein a water-soluble organic material is in contact with the separating functional layer, and the separating functional layer has a boron removal ratio of 95% or more, when seawater at 25° C. having a pH of 6.5, a boron concentration of 5 ppm and a TDS concentration of 3.5% by weight is permeated under an operation pressure of 5.5 MPa.

摘要翻译： 一种复合半透膜，其包含分离功能层，其包含多官能胺与多官能酰卤的反应物，其中水溶性有机材料与分离功能层接触，分离功能层的脱硼率为95 ％以上，当pH为6.5，硼浓度为5ppm，TDS浓度为3.5重量％的25℃的海水在5.5MPa的操作压力下渗透。

公开(公告)号：US20090302919A1

公开(公告)日：2009-12-10

申请号：US12542459

申请日：2009-08-17

申请人： Takao Sasaki

发明人： Takao Sasaki

IPC分类号： H03K5/13

CPC分类号： H03K5/15 ,  H03K2005/00286

摘要： A phase shifter includes a phase shifting unit for operating at a timing at which a clock signal becomes equal to or greater than a threshold value and outputting periodic signals having phases shifted by 90 degrees from each other; a DC voltage setting unit for setting a voltage value of a DC component of the clock signal input into the phase shifting means; and a clock signal slope varying unit for varying a slope of a rising edge of the clock signal.

摘要翻译： 移相器包括：相位移单元，用于在时钟信号变为等于或大于阈值的定时处操作，并输出相位相差90度的周期信号; 直流电压设定单元，用于设定输入到所述相移装置的时钟信号的直流分量的电压值; 以及用于改变时钟信号的上升沿的斜率的时钟信号斜率变化单元。

公开(公告)号：US20090118361A1

公开(公告)日：2009-05-07

申请号：US12299993

申请日：2007-05-16

申请人： Takao Sasaki

发明人： Takao Sasaki

IPC分类号： A61K31/366 ,  C07D311/16 ,  A61P3/10 ,  A61P29/00 ,  A61P35/04 ,  A61P37/06 ,  A61P9/10 ,  A61P3/04

CPC分类号： A61K36/752 ,  A23L33/105 ,  A61K31/352

摘要： A suppressor of the expression of MCP-1 is provided that is excellent in safety and is widely applicable to, for example, foods. The suppressor of the expression of MCP-1 according to the present invention is characterized by containing auraptene. Auraptene is contained in citrus fruits such as Hassaku, Amanatsu, Natsumikan, and grapefruit. Since these citrus fruits have been eaten for a long time, the present invention has no problem in safety. Furthermore, even when added to, for example, foods, auraptene does not impair the flavor thereof because it is substantially tasteless and odorless. Since auraptene has a low calorific value, for example, an obese person or a diabetic patient can ingest it over a long period of time. Auraptene suppresses the expression of MCP-1 at a genetic level (see FIG. 1) and a protein level.

摘要翻译： 提供MCP-1表达的抑制剂，其安全性优异并且广泛适用于例如食品。 根据本发明的MCP-1表达的抑制剂的特征在于含有巯基。 柑橘类水果中含有奥罗丁烯，如Hassaku，Amanatsu，Natsumikan和葡萄柚。 由于这些柑橘类水果长时间食用，本发明的安全性没有问题。 此外，即使添加到例如食品中，由于其基本上无味且无臭，所以紫罗兰烯不会损害其香味。 由于奥来哌啶具有低热值，例如，肥胖者或糖尿病患者可以长时间摄取它。 Auraptene在遗传水平（参见图1）和蛋白质水平抑制MCP-1的表达。

公开(公告)号：US07415250B2

公开(公告)日：2008-08-19

申请号：US10827081

申请日：2004-04-19

申请人： Takao Sasaki ,  Hideharu Shako ,  Hiromi Miyamoto

发明人： Takao Sasaki ,  Hideharu Shako ,  Hiromi Miyamoto

IPC分类号： H04B1/04

CPC分类号： H03F1/3247 ,  H03F1/3294 ,  H03F2200/465 ,  H03F2201/3227 ,  H03F2201/3233 ,  H04L27/368

摘要： Disclosed is a distortion compensating amplifier having a distortion compensator for compensating for distortion of an amplifier by updating distortion compensation coefficients so as to null a difference between a transmit signal and a feedback signal, and subjecting the transmit signal to distortion compensation processing using the distortion compensation coefficients, an amplifier for amplifying the transmit signal, which has undergone distortion compensation, in order to transmit the signal from an antenna, and a feedback unit for inputting an output signal from the amplifier to a distortion compensation coefficient updater in the distortion compensator as the feedback signal. Whether the level of an unwanted-wave signal that penetrates the amplifier from space via an antenna is greater than a set level is monitored. If the level of the unwanted-wave signal is above the set level, processing for updating distortion compensation coefficients is suspended. If the level of the unwanted-wave signal is below the set level, then processing for updating distortion compensation coefficients is resumed.

摘要翻译： 公开了一种失真补偿放大器，其具有失真补偿器，用于通过更新失真补偿系数来补偿放大器的失真，以便使发送信号和反馈信号之间的差值为零，以及使用失真补偿对发送信号进行失真补偿处理 系数，用于放大已经经历失真补偿的发射信号的放大器，以便从天线发射信号;以及反馈单元，用于将来自放大器的输出信号输入到失真补偿器中的失真补偿系数更新器作为 反馈信号。 监测通过天线从空间穿透放大器的不想要的波信号的电平是否大于设定电平。 如果不想要的波信号的电平高于设定电平，则暂停用于更新失真补偿系数的处理。 如果不想要的波信号的电平低于设定电平，则恢复更新失真补偿系数的处理。

公开(公告)号：US20080131580A1

公开(公告)日：2008-06-05

申请号：US11792155

申请日：2005-12-02

申请人： Takao Sasaki ,  Kiyofumi Takayama

发明人： Takao Sasaki ,  Kiyofumi Takayama

IPC分类号： A23L1/212

CPC分类号： A23B7/022 ,  A23D9/00 ,  A23L33/105 ,  A23L33/21

摘要： The present invention relates to a water-soluble dry food containing a plant-origin material as the main ingredient and water-soluble dietary fiber as an additive. The water-soluble dry food of the present invention further contains edible oil. Preferably, as the edible oil, use is made of olive oil, safflower oil, sesame oil or rapeseed oil. Preferably, ashitaba is used as the plant-origin material, whereas indigestible dextrin is used as the water-soluble dietary fiber.

摘要翻译： 本发明涉及以植物来源材料为主要成分和水溶性膳食纤维作为添加剂的水溶性干食品。 本发明的水溶性干性食品还含有食用油。 优选地，作为食用油，使用橄榄油，红花油，芝麻油或菜籽油。 优选地，将ashitaba用作植物来源的材料，而不可消化的糊精用作水溶性膳食纤维。

公开(公告)号：US20060034895A1

公开(公告)日：2006-02-16

申请号：US11220622

申请日：2005-09-08

申请人： Takao Sasaki ,  Yasuko Yamada

发明人： Takao Sasaki ,  Yasuko Yamada

IPC分类号： A61K31/70 ,  A61K47/00

CPC分类号： A61K9/0056 ,  A23L29/231 ,  A23L29/238 ,  A23L29/256 ,  A23L29/262 ,  A23L29/27 ,  A23L29/284 ,  A23L33/00 ,  A23V2002/00 ,  A61K9/0095 ,  A61K31/7004 ,  A23V2250/61 ,  A23V2250/5432 ,  A23V2250/5024 ,  A23V2250/708

摘要： A supplement food which is useful when the diabetic of recuperation at home lapses into low blood glucose condition, and a supplement food for taking in easily, acting quickly to recovering low blood glucose condition, and, moreover, not having durability after recovery. A supplement food having glucose as the principal component, containing glucose in jelly, and contains 10-20 g of glucose in a packaging.

摘要翻译： 当家庭中恢复的糖尿病患者血糖降低的补充食品和用于容易地摄取的补充食物，快速恢复低血糖状况的补充食品，以及恢复后不具有耐久性的补充食品。 以葡萄糖为主要成分的补充食品，含有果冻中的葡萄糖，并在包装​​中含有10-20g的葡萄糖。

公开(公告)号：US06949976B2

公开(公告)日：2005-09-27

申请号：US11022239

申请日：2004-12-23

申请人： Yasuhito Funyu ,  Takao Sasaki ,  Hiromi Miyamoto ,  Takeshi Ohba

发明人： Yasuhito Funyu ,  Takao Sasaki ,  Hiromi Miyamoto ,  Takeshi Ohba

IPC分类号： H03F1/32 ,  H03F1/26

CPC分类号： H03F1/3247

摘要： A distortion compensating amplifier device is disclosed that maintains uniform delay amounts between a transmission input signal and a transmission output signal, even if there is a change in the device characteristics. The distortion compensating amplifier device of a digital predistortion type includes a second delay circuit that delays the transmission input signal; a distortion compensating circuit that performs predistortion compensation on the delayed signal, using a distortion compensating parameter; an amplifier that amplifies the signal subjected to the predistortion compensation; a first delay circuit that further delays the signal delayed by the second delay circuit; and a calculator that calculates the distortion compensating parameter to be used in the predistortion compensation, based on the difference between the signal output from the first delay circuit and the amplified signal.

摘要翻译： 公开了一种失真补偿放大器装置，即使在器件特性有变化的情况下，也能够在发送输入信号和发送输出信号之间保持均匀的延迟量。 数字预失真型的失真补偿放大器装置包括延迟发送输入信号的第二延迟电路; 失真补偿电路，使用失真补偿参数对延迟信号执行预失真补偿; 放大器，用于放大经过预失真补偿的信号; 第一延迟电路，其进一步延迟由所述第二延迟电路延迟的信号; 以及计算器，其基于从第一延迟电路输出的信号与放大信号之间的差异来计算用于预失真补偿的失真补偿参数。

公开(公告)号：US06914639B2

公开(公告)日：2005-07-05

申请号：US10043956

申请日：2002-01-09

申请人： Masaki Yamamoto ,  Takao Sasaki

发明人： Masaki Yamamoto ,  Takao Sasaki

IPC分类号： H04N5/50 ,  H04B1/18 ,  H04B1/26 ,  H04N5/44 ,  H04N5/46 ,  H40N5/50 ,  H40N5/46

CPC分类号： H04N5/44 ,  H04N5/46 ,  H04N21/4263

摘要： A combination tuner includes a switching circuit having three transistors which are selectively turned on and off so that one of a television signal received by a first signal receiving unit using an external antenna that is a high sensitivity antenna, an FM signal received by a second signal receiving unit using an internal antenna that is a low sensitivity antenna, and an FM signal received by the first signal receiving unit using the external antenna is selected according to three-mode band data. Therefore, the combination tuner can select an antenna for receiving a desirable FM signal according to the reception field intensity of the target FM signal so that the FM signal can always be reproduced successfully.

摘要翻译： 组合调谐器包括具有选择性地导通和截止的三个晶体管的开关电路，使得由使用作为高灵敏度天线的外部天线的第一信号接收单元接收的电视信号，由第二信号接收的FM信号 接收单元，使用作为低灵敏度天线的内部天线，以及使用外部天线的由第一信号接收单元接收的FM信号根据三模式频带数据进行选择。 因此，组合调谐器可以根据目标FM信号的接收场强度选择用于接收期望的FM信号的天线，从而可以总是成功地再现FM信号。