Methods and apparatus to access and align sealing discs are disclosed herein. An example apparatus includes a cage of a fluid regulator, where the cage has a central aperture, and a valve stem to be received by the central aperture. The example apparatus also includes a diaphragm coupled to the valve stem, where an integral protrusion of the cage is to constrain a peripheral edge of the diaphragm against a removable portion of a valve body when the cage is coupled to the valve body.