Invention Grant
- Patent Title: Modulators of opioid receptors and methods of use thereof
- Patent Title (中): 阿片类受体的调节剂及其使用方法
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Application No.: US14352294Application Date: 2012-11-07
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Publication No.: US09580409B2Publication Date: 2017-02-28
- Inventor: Scott Malcolm , Carrie Bowen , Laurence Melnick , Linghong Xie
- Applicant: Sunovion Pharmaceuticals Inc.
- Applicant Address: US MA Marlborough
- Assignee: SUNOVION PHARMACEUTICALS, INC.
- Current Assignee: SUNOVION PHARMACEUTICALS, INC.
- Current Assignee Address: US MA Marlborough
- Agency: Heslin Rothenberg Farley & Mesiti P.C.
- International Application: PCT/US2012/063795 WO 20121107
- International Announcement: WO2013/070659 WO 20130516
- Main IPC: C07D403/04
- IPC: C07D403/04 ; C07D401/14 ; C07D403/14 ; C07D487/04 ; C07D487/14 ; C07D498/04 ; C07D471/04 ; C07D405/14 ; C07D487/10 ; C07D491/10 ; A61K31/4178 ; A61K31/4184 ; A61K31/4196 ; A61K31/437 ; A61K31/4439 ; A61K31/454 ; A61K31/501 ; A61K31/551 ; A61K31/553

Abstract:
Provided herein are compounds and methods of synthesis thereof. The compounds provided herein are useful for the treatment, prevention, and/or management of various disorders, such as pain, neurological disorders, psychiatric disorders, and neuromuscular disorders. Compounds provided herein modulate the activity of opioid receptor (e.g., μ-opioid receptor) in the central nervous system or the periphery. Pharmaceutical formulations containing the compounds and their methods of use are also provided herein.
Public/Granted literature
- US20140288050A1 MODULATORS OF OPIOID RECEPTORS AND METHODS OF USE THEREOF Public/Granted day:2014-09-25
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