Invention Grant
- Patent Title: Biomarker for alzheimer's disease or mild cognitive impairment
- Patent Title (中): 阿尔茨海默病或轻度认知障碍的生物标志物
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Application No.: US13880475Application Date: 2011-06-23
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Publication No.: US09581604B2Publication Date: 2017-02-28
- Inventor: Yoshiaki Sato , Ken Aoshima , Francois Bernier
- Applicant: Yoshiaki Sato , Ken Aoshima , Francois Bernier
- Applicant Address: JP Tokyo
- Assignee: Eisai R&D Management Co., Ltd.
- Current Assignee: Eisai R&D Management Co., Ltd.
- Current Assignee Address: JP Tokyo
- Agency: Fish & Richardson P.C.
- Priority: JP2010-235203 20101020; JP2010-282938 20101220
- International Application: PCT/JP2011/064487 WO 20110623
- International Announcement: WO2012/053255 WO 20120426
- Main IPC: G01N33/92
- IPC: G01N33/92 ; G01N33/68
Abstract:
Desmosterol alone, the combination of desmosterol and amyloid beta, the combination of desmosterol and gelsolin and the combination of desmosterol, amyloid beta and gelsolin can be used as in-blood biomarkers for Alzheimer's disease or mild cognitive impairment. A method for evaluating the effect of a candidate for a therapeutic agent to treat Alzheimer's disease or mild cognitive impairment, a method for aiding the diagnosis of Alzheimer's disease or mild cognitive impairment, and a method for diagnosing Alzheimer's disease or mild cognitive impairment are provided in which the biomarkers are used.
Public/Granted literature
- US20130266589A1 Biomarker for Alzheimer`s Disease or Mild Cognitive Impairment Public/Granted day:2013-10-10
Information query
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