发明授权
- 专利标题： Biomarker for alzheimer's disease or mild cognitive impairment
- 专利标题（中）： 阿尔茨海默病或轻度认知障碍的生物标志物
-
申请号： US13880475申请日： 2011-06-23
-
公开(公告)号： US09581604B2公开(公告)日： 2017-02-28
- 发明人: Yoshiaki Sato , Ken Aoshima , Francois Bernier
- 申请人： Yoshiaki Sato , Ken Aoshima , Francois Bernier
- 申请人地址： JP Tokyo
- 专利权人： Eisai R&D Management Co., Ltd.
- 当前专利权人： Eisai R&D Management Co., Ltd.
- 当前专利权人地址： JP Tokyo
- 代理机构： Fish & Richardson P.C.
- 优先权： JP2010-235203 20101020; JP2010-282938 20101220
- 国际申请： PCT/JP2011/064487 WO 20110623
- 国际公布： WO2012/053255 WO 20120426
- 主分类号： G01N33/92
- IPC分类号： G01N33/92 ; G01N33/68
摘要：
Desmosterol alone, the combination of desmosterol and amyloid beta, the combination of desmosterol and gelsolin and the combination of desmosterol, amyloid beta and gelsolin can be used as in-blood biomarkers for Alzheimer's disease or mild cognitive impairment. A method for evaluating the effect of a candidate for a therapeutic agent to treat Alzheimer's disease or mild cognitive impairment, a method for aiding the diagnosis of Alzheimer's disease or mild cognitive impairment, and a method for diagnosing Alzheimer's disease or mild cognitive impairment are provided in which the biomarkers are used.
公开/授权文献
信息查询
IPC分类:
