A printing module of the flexo printing type, is provided with an anilox roller and an impression roller which are set up between two frame parts. Further, the printing module comprises a plate cylinder assembly which is receivable in a plate cylinder holder assembly. The plate cylinder holder assembly is provided with a plate-shaped body part with a supporting ring support surface with a special curve which is symmetrical with respect to a curve plane. Further, each plate cylinder holder assembly comprises a body part support assembly via which the body part is connected with the associated frame part, wherein the body part support assembly is configured for pivoting the body part about a first imaginary pivoting axis and for pivoting the body part about a second imaginary pivoting axis, such as to allow a substantially independent distance setting between the plate cylinder and the anilox roller on one side and between the plate cylinder and the impression roller on the other side.