发明授权
US09586921B2 Burdock fruit extract containing arctigenin at high content and process for producing same
有权
牛蒡果实提取物含有高含量的玉米赤霉菌素及其生产方法
- 专利标题： Burdock fruit extract containing arctigenin at high content and process for producing same
- 专利标题（中）： 牛蒡果实提取物含有高含量的玉米赤霉菌素及其生产方法
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申请号： US13260506申请日： 2010-02-05
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公开(公告)号： US09586921B2公开(公告)日： 2017-03-07
- 发明人: Keiichi Yamamoto , Toshiki Okubo , Satoshi Yomoda , Hiroyasu Esumi , Chika Miyoshi , Shigetoshi Kadota
- 申请人： Keiichi Yamamoto , Toshiki Okubo , Satoshi Yomoda , Hiroyasu Esumi , Chika Miyoshi , Shigetoshi Kadota
- 申请人地址： JP Minato-ku JP Chuo-Ku JP Toyama-shi
- 专利权人： Kracie Pharma, Ltd.,Japan as Represented by President of National Cancer Center,National University Corporation University of Toyama
- 当前专利权人： Kracie Pharma, Ltd.,Japan as Represented by President of National Cancer Center,National University Corporation University of Toyama
- 当前专利权人地址： JP Minato-ku JP Chuo-Ku JP Toyama-shi
- 代理机构： Locke Lord LLP
- 代理商 NIcholas J. DiCeglie, Jr.
- 优先权： JP2009-079590 20090327
- 国际申请： PCT/JP2010/051701 WO 20100205
- 国际公布： WO2010/109961 WO 20100930
- 主分类号： A61K31/365
- IPC分类号： A61K31/365 ; C07D307/33 ; A61K9/16 ; A61K9/20 ; A61K36/28 ; A61K9/19
摘要：
PROBLEM TO BE SOLVEDA burdock fruit extract containing arctigenin at high content and its production method are provided, and both of which are used for treatment of pancreatic cancer.SOLUTIONThe burdock fruit extract containing arctigenin at high content by enzymatically converted arctiin into arctigenin with beta-glucosidase, which is an enzyme occurring endogenously in a burdock fruit, and adding ethanol, extracting, concentrating and then freeze-drying or spray drying.
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