Invention Grant
US09592283B2 Immunological compositions containing attenuated Histophilus somni
有权
含有减毒的Histophilus somni的免疫组合物
- Patent Title: Immunological compositions containing attenuated Histophilus somni
- Patent Title (中): 含有减毒的Histophilus somni的免疫组合物
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Application No.: US14668656Application Date: 2015-03-25
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Publication No.: US09592283B2Publication Date: 2017-03-14
- Inventor: Tammy Kolander , Paulraj Lawrence , Russell Bey
- Applicant: MERIAL, INC.
- Applicant Address: US GA Duluth
- Assignee: MERIAL, INC.
- Current Assignee: MERIAL, INC.
- Current Assignee Address: US GA Duluth
- Agency: Merial Inc.
- Agent Judy Jarecki-Black; Chad Kitchen
- Main IPC: A61K39/102
- IPC: A61K39/102 ; A61K45/06 ; C12N1/36 ; C12N1/38 ; A61K39/00
Abstract:
This disclosure provides attenuated Histophilus somni strains, compositions comprising same, and methods of production and use thereof. The attenuated strains may express lower or no levels of various virulence-associated genes, relative to the corresponding pathogenic bacteria Advantageously, the attenuated Histophilus somni strains may be administered orally, intranasally, intra-tracheally, or subcutaneously.
Public/Granted literature
- US20150273045A1 Immunological Compositions Containing Attenuated Histophilus somni Public/Granted day:2015-10-01
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