- 专利标题: Substituted phthalazin-1 (2H)-one derivatives as selective inhibitors of poly (ADP-ribose) polymerase-1
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申请号: US14647088申请日: 2013-12-23
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公开(公告)号: US09598418B2公开(公告)日: 2017-03-21
- 发明人: Brijesh K. Srivastava , Ranjit C. Desai , Pankaj R. Patel
- 申请人: CADILA HEALTHCARE LIMITED
- 申请人地址: IN Gujarat
- 专利权人: Cadila Healthcare Limited
- 当前专利权人: Cadila Healthcare Limited
- 当前专利权人地址: IN Gujarat
- 代理机构: Nixon & Vanderhye P.C.
- 优先权: IN3742/MUM/2012 20121231
- 国际申请: PCT/IN2013/000794 WO 20131223
- 国际公布: WO2014/102817 WO 20140703
- 主分类号: C07D498/04
- IPC分类号: C07D498/04 ; C07D487/04 ; C07D237/32 ; C07D491/048 ; C07D495/04 ; C07D513/04 ; C07D403/10
摘要:
The present invention relates to novel compounds of general formula (I), their stereoisomers, regioisomers, tautomeric forms and novel intermediates involved in their synthesis, their pharmaceutically acceptable salts, pharmaceutically acceptable solvates and pharmaceutical compositions containing them. The present invention also relates to a process of preparing novel compounds of general formula (I), their stereoisomers, regioisomers, their tautomeric forms, their pharmaceutically acceptable salts, pharmaceutically acceptable solvates, pharmaceutical compositions containing them, and novel intermediates involved in their synthesis.
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