SUBSTITUTED PHTHALAZIN-1 (2H)-ONE DERIVATIVES AS SELECTIVE INHIBITORS OF POLY (ADP-RIBOSE) POLYMERASE-1
    3.
    发明申请
    SUBSTITUTED PHTHALAZIN-1 (2H)-ONE DERIVATIVES AS SELECTIVE INHIBITORS OF POLY (ADP-RIBOSE) POLYMERASE-1 有权
    取代的苯乙酮-1(2H) - 酮衍生物作为聚(ADP-赖酮)聚合酶-1的选择性抑制剂

    公开(公告)号:US20150291603A1

    公开(公告)日:2015-10-15

    申请号:US14647088

    申请日:2013-12-13

    摘要: The present invention relates to novel compounds of general formula (I), their stereoisomers, regioisomers, tautomeric forms and novel intermediates involved in their synthesis, their pharmaceutically acceptable salts, pharmaceutically acceptable solvates and pharmaceutical compositions containing them. The present invention also relates to a process of preparing novel compounds of general formula (I), their stereoisomers, regioisomers, their tautomeric forms, their pharmaceutically acceptable salts, pharmaceutically acceptable solvates, pharmaceutical compositions containing them, and novel intermediates involved in their synthesis.

    摘要翻译: 本发明涉及通式(I)的新型化合物,其立体异构体,区域异构体,互变异构形式和参与其合成的新中间体,其药学上可接受的盐,药学上可接受的溶剂合物和含有它们的药物组合物。 本发明还涉及制备通式(I)的新化合物,其立体异构体,区域异构体,其互变异构形式,其药学上可接受的盐,药学上可接受的溶剂合物,含有它们的药物组合物以及参与其合成的新型中间体的方法。