Invention Grant
- Patent Title: Ultra-stable oligonucleotide-gold and-silver nanoparticle conjugates and method of their preparation
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Application No.: US13437940Application Date: 2012-04-03
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Publication No.: US09605304B2Publication Date: 2017-03-28
- Inventor: Thomas Ming Hung Lee , Kwun Fung Wong , Shea Ping Yip
- Applicant: Thomas Ming Hung Lee , Kwun Fung Wong , Shea Ping Yip
- Applicant Address: HK Hung Hom, Kowloon
- Assignee: The Hong Kong Polytechnic University
- Current Assignee: The Hong Kong Polytechnic University
- Current Assignee Address: HK Hung Hom, Kowloon
- Agency: Duane Morris LLP
- Agent Siegfried J. W. Ruppert
- Main IPC: C12Q1/68
- IPC: C12Q1/68 ; B82Y5/00 ; B82Y15/00
Abstract:
A method for stabilizing conjugates between macromolecule and nanoparticle by forming a thin reinforcement layer over the surface of a nanoparticle after macromolecule chains have attached to the surface of the nanoparticle. The stabilized conjugates can be used in a wide range of applications such as in vitro diagnostics, in vivo imaging and therapeutics, which need to be conducted under various severe or harsh conditions.
Public/Granted literature
- US20130022682A1 Ultra-Stable Oligonucleotide-Gold And-Silver Nanoparticle Conjugates And Method Of Their Preparation Public/Granted day:2013-01-24
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