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1.发明申请Ultra-Stable Oligonucleotide-Gold And-Silver Nanoparticle Conjugates And Method Of Their Preparation 有权超稳定寡核苷酸 - 金和银纳米颗粒结合体及其制备方法公开(公告)号：US20130022682A1
公开(公告)日：2013-01-24
申请号：US13437940
申请日：2012-04-03
Applicant: Thomas Ming Hung Lee , Kwun Fung Wong , Shea Ping Yip
Inventor： Thomas Ming Hung Lee , Kwun Fung Wong , Shea Ping Yip
CPC classification number: C12Q1/6844 , B82Y5/00 , B82Y15/00 , C12Q2563/155
Abstract: A method for stabilizing conjugates between macromolecule and nanoparticle by forming a thin reinforcement layer over the surface of a nanoparticle after macromolecule chains have attached to the surface of the nanoparticle. The stabilized conjugates can be used in a wide range of applications such as in vitro diagnostics, in vivo imaging and therapeutics, which need to be conducted under various severe or harsh conditions.
Abstract translation: 一种用于通过在大分子链连接到纳米颗粒的表面之后在纳米颗粒的表面上形成薄的增强层来稳定大分子和纳米颗粒之间的共轭物的方法。 稳定的缀合物可用于广泛的应用，例如体外诊断，体内成像和治疗，其需要在各种严酷或恶劣的条件下进行。
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2.发明申请Method of detecting vibrio parahaemolyticus via real-time PCR-hybridization 审中-公开通过实时PCR杂交检测副溶血弧菌的方法公开(公告)号：US20090226895A1
公开(公告)日：2009-09-10
申请号：US11896499
申请日：2007-09-04
Applicant: Hang Mei Polly Leung , Shea Ping Yip , Shing Shun Tony To , Lek Hang Constance Lo
Inventor： Hang Mei Polly Leung , Shea Ping Yip , Shing Shun Tony To , Lek Hang Constance Lo
IPC: C12Q1/68
CPC classification number: C12Q1/689 , Y02A50/451 , C12Q2561/113 , C12Q2531/113
Abstract: The present invention relates to an assay and methods for determining the presence of pathogenic V. parahaemolyticus in a sample. Determination should be made by detector. Via the assay, rapid, real-time detection of V. parahaemolyticus is possible.
Abstract translation: 本发明涉及用于测定样品中病原性副溶血弧菌存在的测定法和方法。 检测器应进行测定。 通过测定，快速，实时检测副溶血弧菌是可能的。
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3.发明授权公开(公告)号：US09605304B2
公开(公告)日：2017-03-28
申请号：US13437940
申请日：2012-04-03
Applicant: Thomas Ming Hung Lee , Kwun Fung Wong , Shea Ping Yip
Inventor： Thomas Ming Hung Lee , Kwun Fung Wong , Shea Ping Yip
CPC classification number: C12Q1/6844 , B82Y5/00 , B82Y15/00 , C12Q2563/155
Abstract: A method for stabilizing conjugates between macromolecule and nanoparticle by forming a thin reinforcement layer over the surface of a nanoparticle after macromolecule chains have attached to the surface of the nanoparticle. The stabilized conjugates can be used in a wide range of applications such as in vitro diagnostics, in vivo imaging and therapeutics, which need to be conducted under various severe or harsh conditions.
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