A sunroof structure for a vehicle has a left side frame disposed on a left side of a vehicle body roof, extending along a vehicle front-rear direction, a right side frame disposed on a right side of the vehicle body roof, extending along the vehicle front-rear direction, a roof panel disposed between the left side frame and the right side frame, having a sunroof opening, a sunroof disposed in the sunroof opening and having at least two glass panels arranged next to each other in the vehicle front-rear direction, in which at least a foremost glass panel of the at least two glass panels is configured to be openable and closeable, and a sunroof side rail disposed below a peripheral portion of the sunroof opening, extending along the vehicle front-rear direction, and having a drain groove and a drain portion configured to discharge water accumulated in the drain groove.