Invention Grant
- Patent Title: Modified FGF-21 polypeptides comprising an internal deletion and uses thereof
-
Application No.: US15215329Application Date: 2016-07-20
-
Publication No.: US09631004B2Publication Date: 2017-04-25
- Inventor: Paul E. Morin , Daniel Cohen , Ranjan Mukherjee , Timothy P. Reilly , Rose C. Christian , Dasa Lipovsek , Ray Camphausen , John Krupinski
- Applicant: BRISTOL-MYERS SQUIBB COMPANY
- Applicant Address: US NJ Princeton
- Assignee: BRISTOL-MYERS SQUIBB COMPANY
- Current Assignee: BRISTOL-MYERS SQUIBB COMPANY
- Current Assignee Address: US NJ Princeton
- Agency: LeClairRyan, a professional corporation
- Agent Robin L. Teskin
- Main IPC: A61K38/18
- IPC: A61K38/18 ; A61K39/395 ; C07K14/50 ; A61K45/06 ; A61K47/48 ; A61K38/00
Abstract:
Modified FGF-21 polypeptides and uses thereof are provided, for example, for the treatment of diseases associated with fibrosis. Modified FGF-21 polypeptides are disclosed that contain an internal deletion and optionally replacement peptide, optionally modified with at least one non-naturally-encoded amino acid, and/or optionally fused to a fusion partner.
Public/Granted literature
- US20170029479A1 Modified FGF-21 Polypeptides Comprising an Internal Deletion and Uses Thereof Public/Granted day:2017-02-02
Information query
IPC分类:
