- 专利标题： Isoxazoline hydroxamic acid derivatives as LpxC inhibitors
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申请号： US15304044申请日： 2015-04-22
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公开(公告)号： US09637482B2公开(公告)日： 2017-05-02
- 发明人: Jiping Fu , Xianming Jin , Subramanian Karur , Guillaume Lapointe , Patrick Lee , Zachary Kevin Sweeney
- 申请人： Jiping Fu , Xianming Jin , Subramanian Karur , Guillaume Lapointe , Patrick Lee , Zachary Kevin Sweeney
- 申请人地址： CH Basel
- 专利权人： Novartis AG
- 当前专利权人： Novartis AG
- 当前专利权人地址： CH Basel
- 代理商 Michael G. Smith
- 国际申请： PCT/US2015/027009 WO 20150422
- 国际公布： WO2015/164458 WO 20151029
- 主分类号： C07D417/10
- IPC分类号： C07D417/10 ; C07D261/04 ; A61K31/421 ; A61K45/06 ; C07D413/04 ; A61K31/4439 ; C07D413/10 ; A61K31/422 ; A61K31/5377
摘要：
This invention pertains generally to compounds of Formula I and compositions containing such compounds, as well as methods of using such compounds to treat bacterial infections. In certain aspects, the invention pertains to methods and compositions for treating infections caused by Gram-negative bacteria.
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