Invention Grant
![Substituted imidazo [1,5-a]pyrazines as PDE9 inhibitors](/docs/US/2017-05-09/US09643970B2/abs.jpg.600x600.jpg)
- Patent Title: Substituted imidazo [1,5-a]pyrazines as PDE9 inhibitors
-
Application No.: US14434308Application Date: 2012-10-09
-
Publication No.: US09643970B2Publication Date: 2017-05-09
- Inventor: Niels Svenstrup , Klaus Baek Simonsen , Lars Kyhn Rasmussen , Karsten Juhl , Morten Langgard , Kate Wen , Yazhou Wang
- Applicant: H Lundbeck A/S
- Applicant Address: DK Valby
- Assignee: H. Lundbeck A/S
- Current Assignee: H. Lundbeck A/S
- Current Assignee Address: DK Valby
- Agency: DT Ward, PC
- Agent Donna T. Ward; Heng Zhu
- International Application: PCT/EP2012/069936 WO 20121009
- International Announcement: WO2013/053690 WO 20130418
- Main IPC: A61K31/4985
- IPC: A61K31/4985 ; C07D487/04
![Substituted imidazo [1,5-a]pyrazines as PDE9 inhibitors](/abs-image/US/2017/05/09/US09643970B2/abs.jpg.150x150.jpg)
Abstract:
This invention is directed to compounds, which are PDE9 enzyme inhibitors. The invention provides a pharmaceutical composition comprising a therapeutically effective amount of a compound of the invention and a pharmaceutically acceptable carrier. The present invention also provides processes for the preparation of the compounds of formula (I) The present invention further provides a method of treating a subject suffering from a neurodegenerative disorder comprising administering to the subject a therapeutically effective amount of a compound of formula (I). The present invention further provides a method of treating a subject suffering from a psychiatric disorder comprising administering to the subject a therapeutically effective amount of a compound of formula (I).
Public/Granted literature
- US20150274736A1 PDE9i with imidazo pyrazinone backbone Public/Granted day:2015-10-01
Information query
IPC分类:
