A method and apparatus are presented for transmitting a signal in accordance with an adaptive blind interference alignment (BIA) scheme in a wireless access system. A transmitter configures a first block including desired signals and interference signals on the basis of a number of receivers within a cell and a number of reception modes of the receivers. Further, the transmitter configures a second block including either the desired signals or the interference signals, and configures alignment blocks for each of the receivers by combining the first block with the second block. The transmitter transmits the alignment blocks to the receivers in accordance with transmission symbol patterns corresponding to the alignment blocks. Symbol vectors included in the alignment blocks for each of the receivers are configured to be overlapped between the receivers.