Invention Grant
- Patent Title: Substituted quinuclidines as alpha 7-nicotinic acetylcholine receptor activity modulators
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Application No.: US14068004Application Date: 2013-10-31
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Publication No.: US09657010B2Publication Date: 2017-05-23
- Inventor: Dominik Feuerbach , Mathias Frederiksen , Konstanze Hurth , Bernard Lucien Roy
- Applicant: NOVARTIS AG
- Applicant Address: CH Basel
- Assignee: Novartis AG
- Current Assignee: Novartis AG
- Current Assignee Address: CH Basel
- Agent Shawn D. Britt
- Priority: GB0415746.7 20040714
- Main IPC: C07D453/02
- IPC: C07D453/02 ; C07D487/08
Abstract:
The present invention relates to 1-aza-bicycloalkyl derivatives of formula (I) wherein the substituents are as defined in the specification, to processes for their production, their use as pharmaceuticals in the prevention and treatment of psychotic and neurodegenerative disorders. The claimed compounds act as nicotinic acetylcholine receptors (NACHR) ligands.
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