- 专利标题： Functionalized metal-coated energy converting nanoparticles, methods for production thereof and methods for use
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申请号： US12843188申请日： 2010-07-26
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公开(公告)号： US09662389B2公开(公告)日： 2017-05-30
- 发明人: Tuan Vo-Dinh , Jon Scaffidi , Molly Gregas , Benoit Lauly
- 申请人： Tuan Vo-Dinh , Jon Scaffidi , Molly Gregas , Benoit Lauly
- 申请人地址： US NC Durham
- 专利权人： Duke University
- 当前专利权人： Duke University
- 当前专利权人地址： US NC Durham
- 代理机构： Oblon, McClelland, Maier & Neustadt, L.L.P.
- 主分类号： A61K9/16
- IPC分类号： A61K9/16 ; A61K41/00 ; A61K47/48
摘要：
A functionalized nanoparticle, having a core, optionally having a shell on at least a portion thereof, wherein the core contains a material that can convert applied X-ray energy into emitted UV energy and wherein the shell, when present, contains a plasmonics active material; wherein the nanoparticle has on a surface thereof at least one psoralen compound capable of activation by the emitted UV energy, and the use of the functionalized nanoparticle in a method of treating a cell proliferation disorder such as cancer.