- 专利标题: Vitamin D analogues of pharmaceutical interest
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申请号: US15038303申请日: 2014-11-19
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公开(公告)号: US09663429B2公开(公告)日: 2017-05-30
- 发明人: Roman Perez Fernandez , Samuel Seoane Ruzo , Antonio Mouriño Mosquera , Miguel Maestro Saavedra , Jose Esteban Castelao Fernandez , Pranjal Gogoi
- 申请人: UNIVERSIDADE DE SANTIAGO DE COMPOSTELA , UNIVERSIDADE DA CORUÑA , SERVIZO GALEGO DE SAUDE (SERGAS)
- 申请人地址: ES Santiago de Compostela ES A Coruna ES Santiago de Compostela
- 专利权人: UNIVERSIDADE DE SANTIAGO DE COMPOSTELA,UNIVERSIDADE DA CORUNA,SERVIZO GALEGO DE SAUDE (SERGAS)
- 当前专利权人: UNIVERSIDADE DE SANTIAGO DE COMPOSTELA,UNIVERSIDADE DA CORUNA,SERVIZO GALEGO DE SAUDE (SERGAS)
- 当前专利权人地址: ES Santiago de Compostela ES A Coruna ES Santiago de Compostela
- 优先权: ES201331689 20131120
- 国际申请: PCT/ES2014/070855 WO 20141119
- 国际公布: WO2015/075291 WO 20150528
- 主分类号: A61K31/59
- IPC分类号: A61K31/59 ; C07C35/21 ; A61K45/06 ; A61K31/593
摘要:
The present invention relates to compounds of pharmaceutical interest. More particularly, it relates to compounds of formula (I), to processes for obtaining thereof, to the intermediates of their synthesis and processes for obtaining the latter. The compounds of formula (I) have a certain affinity with the vitamin D receptor, they are active in a similar order to 1,25α-dihydroxyvitamin D3 (1,25D), with the advantage of producing less or no hypercalcemia.
公开/授权文献
- US20160297731A1 VITAMIN D ANALOGUES OF PHARMACEUTICAL INTEREST 公开/授权日:2016-10-13
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