Invention Grant
- Patent Title: Alkyl-amide-substituted pyridyl compounds useful as modulators of IL-12, IL-23 and/or IFNα responses
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Application No.: US15034915Application Date: 2014-01-16
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Publication No.: US09663467B2Publication Date: 2017-05-30
- Inventor: Ryan M. Moslin , David S. Weinstein , Stephen T. Wrobleski , Yanlei Zhang , John S. Tokarski , Michael E. Mertzman , Chunjian Liu
- Applicant: BRISTOL-MYERS SQUIBB COMPANY
- Applicant Address: US NJ Princeton
- Assignee: Bristol-Myers Squibb Company
- Current Assignee: Bristol-Myers Squibb Company
- Current Assignee Address: US NJ Princeton
- Agent Elliott Korsen
- Priority: ARP130104090 20131107
- International Application: PCT/US2014/011769 WO 20140116
- International Announcement: WO2015/069310 WO 20150514
- Main IPC: C07D213/56
- IPC: C07D213/56 ; C07D405/12 ; C07D401/12 ; C07D213/82 ; C07D413/12 ; C07D417/12 ; C07B59/00
Abstract:
Compounds having the following formula (I): or a stereoisomer or a pharmaceutically-acceptable salt thereof, wherein R1, R2, R3, R4, and R5 are as defined herein, are useful in the modulation of IL-12, IL-23 and/or IFNα by acting on Tyk-2 to cause signal transduction inhibition.
Public/Granted literature
- US20160280649A1 ALKYL-AMIDE-SUBSTITUTED PYRIDYL COMPOUNDS USEFUL AS MODULATORS OF IL-12, IL-23 AND/OR IFNalpha RESPONSES Public/Granted day:2016-09-29
Information query
