Invention Grant
- Patent Title: Glycine transporter-1 inhibitors
-
Application No.: US14264731Application Date: 2014-04-29
-
Publication No.: US09663476B2Publication Date: 2017-05-30
- Inventor: Stephen A. Hitchcock , Albert Amegadzie , Wenyuan Qian , Xiaoyang Xia , Scott S. Harried
- Applicant: AMGEN INC.
- Applicant Address: US CA Thousand Oaks
- Assignee: AMGEN INC.
- Current Assignee: AMGEN INC.
- Current Assignee Address: US CA Thousand Oaks
- Agent Elsa D. Lemoine
- Main IPC: C07D295/108
- IPC: C07D295/108 ; C07D241/04 ; C07D295/15 ; C07D241/08

Abstract:
The present invention provides compounds that are glycine transporter 1 (hereinafter referred to as GlyT-1) inhibitors and are therefore useful for the treatment of diseases treatable by inhibition of GlyT1 such as cognitive disorders associated with Schizophrenia, ADHD (attention deficit hyperactivity disorder), MCI (mild cognitive impairment), and the like. Also provided are pharmaceutical compositions containing such compounds and processes for preparing such compounds.
Public/Granted literature
- US20150307457A1 GLYCINE TRANSPORTER-1 INHIBITORS Public/Granted day:2015-10-29
Information query