Invention Grant
- Patent Title: Tricyclic pyrido-carboxamide derivatives as rock inhibitors
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Application No.: US14900228Application Date: 2014-07-01
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Publication No.: US09663529B2Publication Date: 2017-05-30
- Inventor: Mimi L. Quan , Zilun Hu , Cailan Wang
- Applicant: BRISTOL-MYERS SQUIBB COMPANY
- Applicant Address: US NJ Princeton
- Assignee: Bristol-Myers Squibb Company
- Current Assignee: Bristol-Myers Squibb Company
- Current Assignee Address: US NJ Princeton
- Agent Hong Liu
- International Application: PCT/US2014/045008 WO 20140701
- International Announcement: WO2015/002926 WO 20150108
- Main IPC: C07D471/04
- IPC: C07D471/04 ; C07D491/052 ; C07D498/04

Abstract:
The present invention provides compounds of Formula (I): or stereoisomers, tautomers, or pharmaceutically acceptable salts thereof, wherein all the variables are as defined herein. These compounds are selective ROCK inhibitors. This invention also relates to pharmaceutical compositions comprising these compounds and methods of treating cardiovascular, smooth muscle, oncologic, neuropathologic, autoimmune, fibrotic, and/or inflammatory disorders using the same.
Public/Granted literature
- US20160152627A1 TRICYCLIC PYRIDO-CARBOXAMIDE DERIVATIVES AS ROCK INHIBITORS Public/Granted day:2016-06-02
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