- 专利标题： Epimorphic regeneration and related hydrogel delivery systems
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申请号： US14544003申请日： 2014-11-13
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公开(公告)号： US09675607B2公开(公告)日： 2017-06-13
- 发明人: Phillip B. Messersmith , Iossif A. Strehin , Ellen Heber-Katz
- 申请人： Northwestern University , The Wistar Institute of Anatomy and Biology
- 申请人地址： US IL Evanston US PA Philadelphia
- 专利权人： Northwestern University,The Wistar Institute of Anatomy and Biology
- 当前专利权人： Northwestern University,The Wistar Institute of Anatomy and Biology
- 当前专利权人地址： US IL Evanston US PA Philadelphia
- 代理机构： Reinhart Boerner Van Deuren s.c.
- 主分类号： A61K47/48
- IPC分类号： A61K47/48 ; A61K31/4745 ; C12N9/02 ; C08G65/333
摘要：
Methods and compositions are described for enhancing tissue regeneration or wound repair in a mammalian subject comprising a composition comprising (a) a proline hydroxylase inhibitor component or molecule that increases or upregulates HIF1a and (b) a carrier component comprising a hydrogel.
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