Invention Grant
- Patent Title: Quinazoline analogs as receptor tyrosine kinase inhibitors
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Application No.: US13607016Application Date: 2012-09-07
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Publication No.: US09676791B2Publication Date: 2017-06-13
- Inventor: Eli Wallace , George Topalov , Joseph Lyssikatos , Alexandre Buckmelter , Qian Zhao
- Applicant: Eli Wallace , George Topalov , Joseph Lyssikatos , Alexandre Buckmelter , Qian Zhao
- Applicant Address: US CO Boulder
- Assignee: Array BioPharma Inc.
- Current Assignee: Array BioPharma Inc.
- Current Assignee Address: US CO Boulder
- Agency: Viksnins Harris & Padys PLLP
- Agent Corey M. Williams
- Main IPC: C07D239/94
- IPC: C07D239/94 ; C07D498/10 ; C07D401/12 ; C07D413/12 ; C07D413/14 ; C07D417/14 ; C07D498/04 ; C04B35/632

Abstract:
This invention provides quinazoline analogs of Formula I: where A is bonded to at least one of the carbons at the 5, 6, 7 or 8 position of the bicyclic ring, and the ring is substituted by up to two independent R3 groups. The invention also includes methods of using compounds of Formula I as type I receptor tyrosine kinase inhibitors and for the treatment of hyperproliferative diseases such as cancer.
Public/Granted literature
- US09527865B2 Quinazoline analogs as receptor tyrosine kinase inhibitors Public/Granted day:2016-12-27
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