- 专利标题： Factor IXa inhibitors
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申请号： US14652150申请日： 2013-12-16
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公开(公告)号： US09695198B2公开(公告)日： 2017-07-04
- 发明人: Cameron James Smith , Edward Sherer , Louis-Charles Campeau , James Balkovec , William John Greenlee , Derun Li , Liangqin Guo , Tin-Yau Chan , Yi-Heng Chen , Yili Chen , Samuel Chackalamannil , John Qiang Tan , Tomokazu Hirabayashi , Mika Sekioka
- 申请人： Cameron James Smith , Edward Sherer , Louis-Charles Campeau , James Balkovec , William John Greenlee , Derun Li , Liangqin Guo , Tin-Yau Chan , Yi-Heng Chen , Yili Chen , Samuel Chackalamannil , John Qiang Tan , Tomokazu Hirabayashi , Mika Sekioka , MERCK SHARP & DOHME CORP. , MOCHIDA PHARMACEUTICAL CO., LTD.
- 申请人地址： US NJ Rahway JP Tokyo
- 专利权人： Merck Sharp & Dohme Corp.,Mochida Pharmaceutical Co., Ltd.
- 当前专利权人： Merck Sharp & Dohme Corp.,Mochida Pharmaceutical Co., Ltd.
- 当前专利权人地址： US NJ Rahway JP Tokyo
- 代理商 Nicole M. Beeler; Catherine D. Fitch
- 国际申请： PCT/US2013/075231 WO 20131216
- 国际公布： WO2014/099694 WO 20140626
- 主分类号： C07D413/14
- IPC分类号： C07D413/14 ; C07D417/06 ; C07D498/04 ; C07D513/04 ; C07D413/12 ; C07D471/04 ; C07D413/06
摘要：
The present invention provides a compound of Formula (I) where A is a heterocycle ring system and B is a heterocycle ring system or aryl ring system, and pharmaceutical compositions comprising one or more said compounds, and methods for using said compounds for treating or preventing thromboses, embolisms, hypercoagulability or fibrotic changes.
公开/授权文献
- US20150368269A1 Factor IXa Inhibitors 公开/授权日：2015-12-24
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