Invention Grant
- Patent Title: Selective glycosidase inhibitors and uses thereof
-
Application No.: US14129169Application Date: 2012-06-27
-
Publication No.: US09701693B2Publication Date: 2017-07-11
- Inventor: Tong-Shuang Li , Ernest J. Mceachern , David J. Vocadlo , Yuanxi Zhou , Yongbao Zhu , Harold G. Selnick
- Applicant: Tong-Shuang Li , Ernest J. Mceachern , David J. Vocadlo , Yuanxi Zhou , Yongbao Zhu , Harold G. Selnick
- Applicant Address: CA Burnaby US NJ Rahway
- Assignee: Alectos Therapeutics Inc.,Merck Sharp & Dohme Corp.
- Current Assignee: Alectos Therapeutics Inc.,Merck Sharp & Dohme Corp.
- Current Assignee Address: CA Burnaby US NJ Rahway
- Agency: Clark & Elbing LLP
- International Application: PCT/CA2012/050435 WO 20120627
- International Announcement: WO2013/000086 WO 20130103
- Main IPC: C07D513/00
- IPC: C07D513/00 ; C07D513/04 ; C07H9/06 ; C12Q1/37 ; C12Q1/34
Abstract:
The invention provides compounds for selectively inhibiting glycosidases, prodrugs of the compounds, and pharmaceutical compositions including the compounds or prodrugs of the compounds. The invention also provides methods of treating diseases and disorders related to deficiency or overexpression of O-GlcNAcase, accumulation or deficiency of O-GlcNAc.
Public/Granted literature
- US20140275022A1 SELECTIVE GLYCOSIDASE INHIBITORS AND USES THEREOF Public/Granted day:2014-09-18
Information query
