A method, a system, and a computer-implemented method for performing multi-level deduplication of data are disclosed. A zone stamp is generated for each zone in a plurality of zones contained in at least one data stream. The zone stamp is compared to another zone stamp. The zone stamp and another zone stamp represent zones in the plurality of zones. The comparison is performed for zones at corresponding zone levels based on a determination that a zone stamp of a zone of a preceding zone level is not similar to another zone stamp of another preceding zone level. The zone at the preceding zone level includes at least one zone of a next zone level having a size smaller than or equal to a size of the zone of the preceding zone level. The zone and another zone are deduplicated based on a determination that the zone stamp is similar to another zone stamp.