A computing system includes: a memory computing block configured to: identify a partial data computing (PDC) command, a data mask, a partial data, or a combination thereof based on decoding a data packet, compute a computation result for identifying a portion of a read data to be modified according to the PDC command, the data mask, the partial data, or a combination thereof, generate a merge result based on modifying the portion of the read data according to the computation result, and a memory interface, coupled to the memory computing block, configured to transmit the merge result.