- 专利标题: Methods of treatment using anti-GDF15 antibodies
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申请号: US14863870申请日: 2015-09-24
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公开(公告)号: US09725505B2公开(公告)日: 2017-08-08
- 发明人: Lorena Lerner , Sandra Abbott , Ailin Bai , Ting Chen , Maria I. Chiu , Qing Liu , Laura Poling , Nianjun Tao , Solly Weiler , Zhigang Weng , William M. Winston, Jr. , Jeno Gyuris
- 申请人: AVEO Pharmaceuticals, Inc.
- 申请人地址: US MA Cambridge
- 专利权人: AVEO Pharmaceuticals, Inc.
- 当前专利权人: AVEO Pharmaceuticals, Inc.
- 当前专利权人地址: US MA Cambridge
- 代理机构: Goodwin Procter LLP
- 主分类号: A61K39/395
- IPC分类号: A61K39/395 ; C07K16/22 ; A61K45/06 ; A61K39/00
摘要:
Monoclonal antibodies that bind and inhibit the activity of human GDF15 are disclosed. The antibodies can be used to treat body weight loss, including cachexia, associated with the over-expression of human GDF15.
公开/授权文献
- US20160083465A1 ANTI-GDF15 ANTIBODIES 公开/授权日:2016-03-24
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