Embodiments described herein provide a method of fragmenting a large message into, for example, numbered packets for sending the message in a packet based communication system, such as in a ZigBee wireless network. Each packet may have a predetermined size and may include a MAC address, a network header of a variable size, and fragmented message data. The fragmented message data can be configured to be smaller than the available space in the packet so that the packet can be sent, for example, when the size of the header increases.