The invention relates to the display technology field, and particularly to a wire grid polarizer, a manufacturing method thereof, a display panel and a display device. The wire grid polarizer comprises a substrate, in which wire grid structures are arranged at intervals in an array, to allow light to penetrate from the grid pitches thereof, with the other area except the wire grid structures of the substrate being a continuous opaque area. Due to the wire grid polarizer being provided with the wire grid structures arranged at intervals in a array, local light transmitting areas can be formed, and light emergence can be controlled more flexibly. A display panel using the wire grid polarizer can effectively lower the light absorption rate, also avoid peripheral light leakage in a non-subpixel area, and prevent the light leakage of the pixels themselves; correspondingly, a display device using the display panel can improve the light utilization rate, and achieve a good display effect.