Invention Grant
- Patent Title: IDO inhibitors
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Application No.: US14897668Application Date: 2014-07-01
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Publication No.: US09765018B2Publication Date: 2017-09-19
- Inventor: Jay A. Markwalder , Steven P. Seitz , James Aaron Balog , Audris Huang , Sunil Kumar Mandal , David K. Williams , Amy C. Hart , Jennifer Inghrim
- Applicant: BRISTOL-MYERS SQUIBB COMPANY
- Applicant Address: US NJ Princeton IN Bangalore, Karnataka US NJ Princeton
- Assignee: Bristol-Myers Squibb Company,Syngene International Limited,Bristol-Myers Squibb Company
- Current Assignee: Bristol-Myers Squibb Company,Syngene International Limited,Bristol-Myers Squibb Company
- Current Assignee Address: US NJ Princeton IN Bangalore, Karnataka US NJ Princeton
- Agent Serena Farquharson-Torres; Elliott Korsen
- International Application: PCT/US2014/044992 WO 20140701
- International Announcement: WO2015/002918 WO 20150108
- Main IPC: C07C275/42
- IPC: C07C275/42 ; C07C311/51 ; C07D213/75 ; C07D257/04 ; C07D401/04 ; A61K31/18 ; A61K31/41 ; A61K31/44 ; C07D213/79 ; C07D307/86 ; A61K31/196 ; A61K31/277 ; A61K31/343 ; A61K31/4418 ; A61K31/444 ; A61K45/06 ; C07C311/09 ; C07D307/79
Abstract:
There are disclosed compounds of formula (I) that modulate or inhibit the enzymatic activity of indoleamine 2,3-dioxygenase (IDO), pharmaceutical compositions containing said compounds and methods of treating proliferative disorders, such as cancer, viral infections and/or inflammatory disorders utilizing the compounds of the invention.
Public/Granted literature
- US20160137595A1 IDO INHIBITORS Public/Granted day:2016-05-19
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