A torque requesting module generates a first torque request for a spark ignition engine based on driver input. A torque conversion module converts the first torque request into a second torque request. A setpoint control module generates air and exhaust setpoints for the spark ignition engine based on the second torque request. A model predictive control (MPC) module identifies sets of possible target values based on the air and exhaust setpoints, generates predicted parameters based on a model of the spark ignition engine and the sets of possible target values, respectively, selects one of the sets of possible target values based on the predicted parameters, and sets target values based on the possible target values of the selected one of the sets. A throttle actuator module controls opening of a throttle valve based on a first one of the target values.