- 专利标题: Screening process for finding samples having a functionality disorder of the GPIb-von willebrand factor interaction
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申请号: US13779904申请日: 2013-02-28
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公开(公告)号: US09766234B2公开(公告)日: 2017-09-19
- 发明人: Juergen Patzke
- 申请人: Siemens Healthcare Diagnostics Products GmbH
- 申请人地址: DE Marburg
- 专利权人: SIEMENS HEALTHCARE DIAGNOSTICS PRODUCTS GMBH
- 当前专利权人: SIEMENS HEALTHCARE DIAGNOSTICS PRODUCTS GMBH
- 当前专利权人地址: DE Marburg
- 代理机构: Slayden Grubert Beard PLLC
- 优先权: EP12158022 20120305
- 主分类号: G01N33/566
- IPC分类号: G01N33/566 ; G01N33/86
摘要:
The invention relates to a screening process for determining a disordered von Willebrand factor (VWF)-GPIb interaction in a patient's sample. This comprises contacting the sample with isolated GPIb.alpha. protein, with VWF protein and with a solid phase associated with an antibody specific for said isolated GPIb.alpha. protein, and determining complex formation.
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