An apparatus includes processing circuitry to perform one or more arithmetic operations for generating a result value based on at least one operand. For at least one arithmetic operation, the processing circuitry is responsive to programmable significance data indicative of a target significance for the result value, to generate the result value having the target significance. For example, this allows programmers to set a significance boundary for the arithmetic operation so that it is not necessary for the processing circuitry to calculate bit values having a significance outside the specified boundary, enabling a performance improvement.