A method and device for performing interference control are provided. The method includes: network side device determines traffic load parameter value of each cell and the measurement parameter between the base stations which random two cells belongs to; For the two cells, the network side device determines an interference control threshold according to the traffic load parameter value of the two cells, and compares the determined the measurement parameter with the interference control threshold, and performs cluster partition according to the comparing result. The network side device performs interference control according to the partitioned cluster. Because the factor of cell traffic load is considered in performing TDD cross link interference control, thus the cross link interference in TDD networking is reduced.