- 专利标题： Stabilized solid medicinal forms containing active ingredient and method for the production thereof
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申请号： US12441629申请日： 2007-09-14
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公开(公告)号： US09775807B2公开(公告)日： 2017-10-03
- 发明人: Peter Gruber , Dirk Spickermann
- 申请人： Peter Gruber , Dirk Spickermann
- 申请人地址： DE Neuenburg
- 专利权人： Losan Pharma GmbH
- 当前专利权人： Losan Pharma GmbH
- 当前专利权人地址： DE Neuenburg
- 代理机构： Smith Patent LLC
- 代理商 Chalin A. Smith
- 优先权： EP06020008 20060925
- 国际申请： PCT/EP2007/008006 WO 20070914
- 国际公布： WO2008/037359 WO 20080403
- 主分类号： A61K47/12
- IPC分类号： A61K47/12 ; A61K47/02 ; A61K47/26 ; A61P43/00 ; A61K9/20 ; A61K9/16
摘要：
The invention relates to solid medicinal forms containing at least one active ingredient and at least one pharmaceutically compatible, water soluble drying agent which is selected from the group consisting of trimagnesium dicitrate and/or calcium chloride, the solid medicinal form having a drying loss of at most 6% and a relative equilibrium moisture content of 25% or less. The invention also relates to solid medicinal forms containing a moisture-sensitive active ingredient and trimagnesium dicitrate.
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