A method implemented by at least one processor includes receiving a plurality of operating parameters of a pumping system, wherein the pumping system has a plurality of pump-units powered by a generator-unit. The operating parameters include a pump-unit parameter and a generator-unit parameter. The method also includes receiving reference data of the pumping system, wherein the reference data includes measurements from the pumping system representative of performance of the plurality of pump-units. The method also includes determining one or more health parameters corresponding to one or more pump-units based on the plurality of operating parameters and the reference data. The method further includes modifying one or more input parameters of the generator-unit based on the one or more health parameters for continued operation of the pumping system.