Invention Grant
- Patent Title: Polynucleotides encoding IL-17/IL-23 bispecific, IL-17A/F and IL-23p19 antibodies
-
Application No.: US14576278Application Date: 2014-12-19
-
Publication No.: US09783606B2Publication Date: 2017-10-10
- Inventor: Brenda L. Stevens , Alison Witte , Mark W. Rixon , Josephine M. Cardarelli , Thomas D. Kempe , Scott R. Presnell , Mohan Srinivasan , Susan C. Wong , Guodong Chen , Hui Wei , Stanley R. Krystek , Lumelle A. Schneeweis , Paul O. Sheppard , Indrani Chakraborty
- Applicant: BRISTOL-MYERS SQUIBB COMPANY
- Applicant Address: US NJ Princeton
- Assignee: Bristol-Myers Squibb Company
- Current Assignee: Bristol-Myers Squibb Company
- Current Assignee Address: US NJ Princeton
- Agent Brian J. Walsh
- Main IPC: C12N15/09
- IPC: C12N15/09 ; C07K16/24 ; C07K16/46 ; A61K39/00
Abstract:
The present invention relates to antagonizing the activity of IL-17A, IL-17F and IL-23 using bispecific antibodies that comprise a binding entity that is cross-reactive for IL-17A and IL-17F and a binding entity that binds IL-23p19. The present invention relates to novel bispecific antibody formats and methods of using the same.
Public/Granted literature
- US20150099278A1 POLYNUCLEOTIDES ENCODING ANTIBODIES Public/Granted day:2015-04-09
Information query
IPC分类:
