Invention Grant
- Patent Title: Positive allosteric modulators and silent allosteric modulators of the Mu opioid receptor
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Application No.: US14758908Application Date: 2013-12-20
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Publication No.: US09784740B2Publication Date: 2017-10-10
- Inventor: Neil Burford , Andrew Alt
- Applicant: BRISTOL-MYERS SQUIBB COMPANY
- Applicant Address: US NJ Princeton
- Assignee: Bristol-Myers Squibb Company
- Current Assignee: Bristol-Myers Squibb Company
- Current Assignee Address: US NJ Princeton
- Agent Warren K. Volles
- International Application: PCT/US2013/077018 WO 20131220
- International Announcement: WO2014/107344 WO 20140710
- Main IPC: G01N33/566
- IPC: G01N33/566
Abstract:
Disclosed are positive allosteric modulators (PAMs) and silent allosteric modulators (SAMs) for mu (μ)-opioid receptors that may be useful for the treatment of pain, either alone or in combination with orthosteric opioid receptor agonists. Methods for treating pain and modulating mu (μ)-opioid receptors are also disclosed.
Public/Granted literature
- US20150338404A1 POSITIVE ALLOSTERIC MODULATORS AND SILENT ALLOSTERIC MODULATORS OF THE Mu OPIOID RECEPTOR Public/Granted day:2015-11-26
Information query
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