Invention Grant
- Patent Title: N-(monocyclic aryl),N'-pyrazolyl-urea, thiourea, guanidine and cyanoguanidine compounds as TrkA kinase inhibitors
-
Application No.: US14442604Application Date: 2013-11-12
-
Publication No.: US09790210B2Publication Date: 2017-10-17
- Inventor: Steven Wade Andrews , James F. Blake , Barbara J. Brandhuber , Timothy Kercher , Shannon L. Winski
- Applicant: Array BioPharma Inc.
- Applicant Address: US CO Boulder
- Assignee: Array BioPharma Inc.
- Current Assignee: Array BioPharma Inc.
- Current Assignee Address: US CO Boulder
- Agency: Viknins Harris Padys Malen LLP
- International Application: PCT/US2013/069732 WO 20131112
- International Announcement: WO2014/078325 WO 20140522
- Main IPC: C07D231/00
- IPC: C07D231/00 ; C07D403/00 ; C07D401/00 ; C07D211/72 ; C07D413/00 ; C07D405/12 ; C07D403/12 ; C07D401/14 ; C07D231/40 ; C07D231/44 ; C07D401/04 ; C07D413/12 ; C07D231/52 ; C07D401/12 ; C07D405/04 ; A61K31/4155

Abstract:
Compounds of Formula (I) or stereoisomers, tautomers, or pharmaceutically acceptable salts, solvates or prodrugs thereof, wherein Ring A, Ring C and X are as defined herein, are inhibitors of TrkA kinase and are useful in the treatment of diseases which can be treated with a TrkA kinase inhibitor such as pain, cancer, inflammation/inflammatory diseases, neurodegenerative diseases, certain infectious diseases, Sjogren's syndrome, endometriosis, diabetic peripheral neuropathy, prostatitis or pelvic pain syndrome.
Public/Granted literature
Information query