Methods and apparatuses are provided for performing carrier aggregation (CA) using a plurality of almost blank subframe (ABS) patterns in a macro enhanced Node B (eNB) of a wireless communication system connected to a heterogeneous network. An ABS pattern having a different pattern is determined for each component carrier (CC), when two or more carriers are deployed in each of the macro eNB and at least one small cell eNB. A serving cell for each user equipment (UE) is determined for each CC, from among a macro cell and a small cell. CA is performed for data transmission to each UE using the determined ABS pattern, in accordance with each determined serving cell.