Invention Grant
- Patent Title: Amide compound and pharmaceutical comprising same
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Application No.: US15100866Application Date: 2014-12-09
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Publication No.: US09796677B2Publication Date: 2017-10-24
- Inventor: Motomu Kanai , Yohei Soma , Tadamasa Arai , Takushi Araya
- Applicant: JAPAN SCIENCE AND TECHNOLOGY AGENCY
- Applicant Address: JP Kawaguchi-shi
- Assignee: JAPAN SCIENCE AND TECHNOLOGY AGENCY
- Current Assignee: JAPAN SCIENCE AND TECHNOLOGY AGENCY
- Current Assignee Address: JP Kawaguchi-shi
- Agency: Oblon, McClelland, Maier & Neustadt, L.L.P.
- Priority: JP2013-254908 20131210; JP2014-112179 20140530
- International Application: PCT/JP2014/082521 WO 20141209
- International Announcement: WO2015/087865 WO 20150618
- Main IPC: A61K31/44
- IPC: A61K31/44 ; A61K31/505 ; C07D213/81 ; C07D239/28 ; C07D239/30

Abstract:
Provided is a novel compound which has an excellent Aβ aggregation inhibitory effect and is useful as a pharmaceutical. An amide compound represented by the formula (1) or a salt thereof, wherein Z represents CH or N; A and B are the same or different and each represents —CH2—, —O—, —S—, or —NH—; R1 and R2 are the same or different and each represents a branched alkyl group, a branched alkenyl group, an optionally substituted aromatic hydrocarbon group, an optionally substituted aralkyl group, an optionally substituted cycloalkyl group, or an optionally substituted aromatic heterocyclic group; and R3 represents a branched alkyl group, a branched alkenyl group, an optionally substituted cycloalkyl group, or an optionally substituted aralkyl group.
Public/Granted literature
- US20160297764A1 AMIDE COMPOUND AND PHARMACEUTICAL COMPRISING SAME Public/Granted day:2016-10-13
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