- 专利标题: Method for deriving melanocytes from the hair follicle outer root sheath and preparation for grafting
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申请号: US14354545申请日: 2012-10-29
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公开(公告)号: US09801977B2公开(公告)日: 2017-10-31
- 发明人: Vuk Savkovic , Christina Dieckmann , Jan-Christoph Simon , Michaela Schulz-Siegmund , Michael Hacker
- 申请人: Vuk Savkovic , Christina Dieckmann , Jan-Christoph Simon , Michaela Schulz-Siegmund , Michael Hacker
- 申请人地址: DE Leipzig
- 专利权人: UNIVERSITÄT LEIPZIG
- 当前专利权人: UNIVERSITÄT LEIPZIG
- 当前专利权人地址: DE Leipzig
- 代理机构: Faegre Baker Daniels LLP.
- 优先权: EP11186944 20111027; EP12182385 20120830
- 国际申请: PCT/EP2012/071418 WO 20121029
- 国际公布: WO2013/060899 WO 20130502
- 主分类号: C12N5/071
- IPC分类号: C12N5/071 ; A61K35/36 ; A61L27/38 ; A61L27/60
摘要:
The present invention relates to the field of biology and medicine, and more specifically, to the field of stem-cell biology, involving producing or generating melanocytes from stem-cells and precursors derived from human hair root. Additionally, the present invention relates to the materials and method for producing autografts, homografts or allografts comprising melanocytes in general, as well as the materials and methods for producing autografts, homografts and allografts comprising melanocytes for the treatment of diseases related to depigmentation of the skin and for the treatment of scars.
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