A system and a method of sampling an event signal using multiple clocking signals each provided in a separate candidate clock domain each of which also receives points in time from a master clock. From each candidate clock domain, clocked by the individual clocking signals, pairs of a received point in time and event signal value are fed to a master clock domain. In the master clock domain, the values of the event signal may be determined over time as a function of master clock time. This may be used for synchronizing operation in the master clock domain of e.g. packet time stamping with an overall time defined by the event signal. Using multiple clocking signals for the sampling, a much more precise sampling of the event signal is facilitated.